Human Microbiota - Xenobiotics Interactions Lab
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Our Vision
The Human Microbiota – Xenobiotics Interactions Lab at ITQB NOVA investigates the effects of trace elements, medications, and other xenobiotics on the composition and function of gut microbiota, as well as their impact on the host.
This is achieved through a combination of systems-based approaches and tailored molecular and biochemical methods.
Selected Publications
High-throughput anaerobic screening for identifying compounds acting against gut bacteria in monocultures or communities.
Nature Protocols, 1-32, 2023
P. Müller, J. de la Cuesta-Zuluaga, M. Kuhn, M. Baghai Arassi, T. Treis, S. Blasche, M. Zimmermann, P. Bork, K. R. Patil, A. Typas, S. Garcia-Santamarina#, L. Maier#. #co-corresponding
Consistency across multi-omics layers in a drug-perturbed gut microbial community.
Molecular Systems Biology, e11525, 2023
S. Wuyts, R. Alves, M. Zimmermann-Kogadeeva, S. Nishijima, S. Blasche, Marja Driessen, P. E. Geyer, R. Hercog, E. Kartal, L. Maier, J. B. Müller, S. Garcia-Santamarina, T. S. B. Schmidt, D. C. Sevin, A. Telzerow, P. V. Treit, T. Wenzel, A. Typas, K. R. Patil, M. Mann, M. Kuhn, P. Bork
Unravelling the collateral damage of antibiotics on gut bacteria.
Nature, 599, 120–124, 2021
L. Maier, C. V. Goemans, J. Wirbel, M. Kuhn, C. Eberl, M. Pruteanu, P. Müller, S. Garcia-Santamarina, E. Cacace, B. Zhang, C. Gekeler, T. Banerjee, E. E. Anderson, A. Milanese, U. Löber, S. K. Forslund, K. R. Patil, M. Zimmermann, B. Stecher, G. Zeller, P. Bork, A. Typas
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